Cucumis sativus (cucumber): a review on its pharmacological activity


  • Tripti Sahu Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg (CG)
  • Jyoti Sahu Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg (CG)


Cucumis sativus, Phytoconstituents, Pharmacological activity


Medicinal plants have been used for centuries, and numerous cultures still rely on plants for their primary health care needs. In the recent past there has been a tremendous increase in the use of plant based health products in developing as well as developed countries resulting in an exponential growth of herbal products globally. The present article gives an account of such a medicinally important of Cucumis sativus belonging to family Cucurbitaceae which comprise both wild and cultivated species and is consumed in different ways like vegetable and salads, but less is known about its medicinal importance. Phytochemical analysis of these plants confirms the presence of various phytochemicals like tannins, cardiac glycosides, terpenoides, carbohydrates, resins, Saponins and phytosterols. While other phtochemicals like alkaloids, flavonoids, glycosides, steroidal terpenes and phylobatamins were found to be cucumber fruits. The plant exhibits various pharmacological activities such as anti-bacterial activity, antifungal activity, cytotoxic activity, Antacid & Carminative activity,  Activity against ulcerative colitis ,Hepetoprotective activity, Hypoglycemic and Hypolipidemic activity, Wound healing activity   etc. A study on safety profile suggests the plant to be safe for its therapeutic uses.


Download data is not yet available.


Kessler RC, Eisenberg DM, et al, “Annals of Internal Medicines”2001,135(4): 262-8

Global Annual Report, Department of ISM andH, 1999:1

Sucher NJ, Carles MC et al., “Genome-based approaches to the authentication of medicinal plants. Planta Medica”, 2008, 74(6):603–623.

Calixto JB, “Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)”, Brazilian Journal of Medicine and Biological Research, 2000, 33:179-189.

Ernst E, Coon Thompson “Clinical Pharmacological and Therapeutics”, 2001, 70(6): 497-504.

Gottschalck TE and Breslawec HP. International Cosmetic Ingredient Dictionary and Handbook. 14ed. Washington, DC: Personal Care Products Council, 2012.

Food and Drug Administration (FDA). Frequency of use of cosmetic ingredients. FDA Database.2011. Washington, DC: FDA.Updated Feb 25.

Personal Care Products Council. 1-10-2012. Concentration of use by FDA Product Category: Cucumis sativus-derived ingredients. Unpublished data submitted by Personal Care Products Council. 3 pages.

Bremmer HJ, Prud'homme de Lodder LCH, and Engelen JGM. Cosmetics Fact Sheet: To assess the risks for the consumer; Updated version for ConsExpo 4. 2006. Report No. RIVM 320104001/2006. pp. 1-77.

Johnsen MA. The influence of particle size. Spray Technology and Marketing. 2004; November:24-27.

Longo Gennaro, “Extraction technology for medicinal and aromatic Plant”, United Nations Industrial Development Organization and the International Centre for Science and High Technology, 2008: 6-8

Lippincott W, et al, W, et al, “Pharmacology”, 4th edition, Wolters Kluwer Health, New Delhi, 2009, 499.

Merrian-Webster, Webster's Medical Desk Dictionary, 1986.

Tripathi KD, “Essentials of Medical Pharmacology”, 6th edition, Jaypee Brothers Medical, New Delhi, 2008, 185.

Rang HP, Dale MM, “Pharmacology”, 6th Edition, Churchill Livingstone Elsevier, 2007, 502-3

Ankita S., Kaur P., and Gupta R. Phytochemical screening and antimicrobial assay of various seeds extracts of Cucurbitaceae Family. International Journal of Applied Biology & Pharmaceutical Technology. Volume 3, Issue 3 (2012): 401-409

Patil K., Kandhare A., Bhise D. Effect of aqueous extract of Cucumis sativus Linn. fruit in ulcerative colitis in laboratory animals. Asian Pacific Journal of Tropical Biomedicine (2012): S962-S969.

Heidari H., Kamalinejad M., Eskandari M. Hepatoprotective activity of Cucumis sativus against cumene hydroperoxide induced-oxidative stress. Research in Pharmaceutical Sciences, 2012; 7(5): S936-S939.

Sharmin R., Khan M., Akhter M., Alim A., Islam A., and Ahmed M. Hypoglycemic and Hypolipidemic Effects of Cucumber, White Pumpkin and Ridge Gourd in Alloxan Induced Diabetic Rats. J. Sci. Res. 5 (1), 161-170.

Mallik J., Akhter R., Phytochemical Screening and In-vitro Evaluation of Reducing Power, Cytotoxicity and Anti-Fungal Activities of Ethanol Extracts of Cucumis sativus. International Journal of Pharmaceutical & Biological Archives 2012; 3(3): 555-560.

Yawalkar K.S., 1985. Cucurbitaceous or vine crops. In: Vegetable crops of India Agric. Horticultural Publishing House, Nagpur, India. pp. 150-158.

Cucumber Production in Green houses Published by the University of Alaska Fairbanks Cooperative Extension Service in cooperation with the United States Department of Agriculture. The University of Alaska Fairbanks is an affirmative action/equal opportunity employer and educational institution. ©2014 University of Alaska Fairbanks. 11-90/WV/7-14 Revised October 2013

Sharma S., Dwivedi J., Paliwal S., Evaluation of antacid and carminative properties of Cucumis sativus under simulated conditions. Scholars Research Library Der Pharmacia Lettre, 2012, 4 (1): 234-239.



How to Cite

Sahu, T., & Sahu, J. (2015). Cucumis sativus (cucumber): a review on its pharmacological activity. Journal of Applied Pharmaceutical Research, 3(1), 04-09. Retrieved from